Q517--Bayesian-Guided medication dosing software 660-27-1-062-0002

Sources Sought Notice Sources Sought Notice Sources Sought Notice *= Required Field Sources Sought Notice Sources Sought Notice Bayesian Dosing Software (Single Site Standalone License) Disclaimer: This Request for Information (RFI) is issued solely for market research information and planning purposes and does not constitute a solicitation. All information received in response to this RFI that is marked as proprietary will be handled accordingly. Responses to this notice are NOT offers and cannot be accepted by the Government to form a binding contract. Responders are solely responsible for all expenses associated with responding to this RFI. Information Requested from Industry: In response to the Sources Sought, interested Contractors shall submit the following information and any Capabilities/Qualifications Statement to include but not limited to an overview of proposed solution(s) and a description of the product your company possesses in accordance with the Statement of Work draft / Salient Characteristics List. Responses to market research table questionnaire shall be submitted. If this information is not provided, then it will be assumed the entire requirement cannot be met. Description of Requirement: The Department of Veterans Affairs, Veterans Health Administration (VHA), Network Contracting Office 19 (NCO 19) is conducting a market survey and is seeking potential sources for a Bayesian Dosing Software, including single site standalone licensing. This Sources Sought Notice is issued for information and planning purposes only. This is not a solicitation or a request for proposal and shall not be construed as an obligation or commitment by the Government. An award will not be made on any offers submitted in response to this notice, and it shall not be implied that the Government is committed to providing any solicitation or award following this notice. The Government will not pay for any information received in response to this request, nor will the Government compensate a respondent for any costs incurred in developing the information provided. Requirement Item: Bayesian Dosing Software Single Site - Standalone Licensing STATEMENT OF WORK Introduction and Overview This statement of work is for a subscription to a Bayesian-guided medication dosing software from a contractor that can provide licensing rights. This subscription is to ensure clinicians have access to a reliable web-based therapeutic drug dosing and monitoring tool for complex clinical situations that require careful drug therapy evaluation and adjustment in a systematic and efficient manner. The software will include important pharmacokinetic parameters and empiric and patient-specific dosing recommendations; allow for graphical prediction and projection of theoretical doses at any drug dosing interval in order to optimize and achieve therapeutic drug levels; provide local storage of data and references for primary literature of clinicals models used; and lastly, be highly customizable, HIPAA and GDPR compliant, and meet VA information security requirements by only providing patient de-identification information on the web-based platform. Must be fully compliant with the IDSA/ASHP Vancomycin 2020 guidelines. Background Intravenous vancomycin remains an important first-line antibiotic used for treatment of serious methicillin-resistant Staphylococcus aureus (MRSA) infections. Recent Consensus Guidelines (Rybak MJ et al, AM J HEALTH-SYST PHARM, March 2020) for vancomycin therapeutic monitoring now recommend vancomycin dose optimization preferably using a Bayesian-guided software to achieve individualized targeted concentrations that maximize clinical efficacy while minimizing renal toxicity. Veterans Affairs Healthcare Systems are complex in scope of services; thus, clinical providers require access to a validated, systematic, and intuitive clinical tool to dose and monitor drug therapy safely. Scope of Work The contractor shall provide all resources necess...