Leica Microsystems Stellaris Microscope System with Confocal 3D Sted

REQUEST FOR QUOTATION (RFQ) / COMBINED SYNOPSIS-SOLICITATION Solicitation Number: 75N98026Q00857 Notice Type: Combined Synopsis Title: Stellaris Microscope System with Confocal 3D-STED, Film and Spectral Multiplexing Imaging Capabilities - Brand name or Equal Posted Date: July 22, 2026 Response Date: July 31, 2026, 11:00 AM Eastern Daylight Time Set-Aside: None NAICS Code: 334516 – Analytical Laboratory Instrument Manufacturing PSC Code: 6640 – Laboratory Equipment and Supplies 1. GENERAL INFORMATION This is a combined synopsis/solicitation for commercial products prepared in accordance with the FAR Subpart 12.6, as supplemented with additional information included in this notice, and in conjunction with FAR Part 12. This announcement constitutes the only solicitation; quotations are being requested, and a separate written solicitation will not be issued. The National Institutes of Health (NIH), National Heart, Lung and Blood Institute (NHLBI), Intends to acquire one (1) microscope system, including automation, software, installation, startup, training, warranty, and manufacturer-supported service, in accordance with the requirements set forth herein. This acquisition is being conducted as an open market purchase. The Government intends to award a Firm-Fixed-Price Purchase Order resulting from this solicitation. 2. DESCRIPTION OF REQUIREMENT 2.1 Background The NHLBI Light Microscopy Core requires acquisition of a state-of-the-art laser-scanning microscope to support advanced cellular and subcellular imaging for investigators within the NHLBI Division of Intramural Research (DIR). The proposed system will replace a 12-year-old Leica SP8 microscope, which will be traded in to offset the cost of the new instrument and ensure continuity of ongoing research projects. The new platform will provide substantial improvements in sensitivity, spatial resolution, and overall imaging performance, while expanding the Core’s ability to perform super-resolution imaging, fluorescence lifetime measurements, and highly multiplexed fluorescence imaging. This instrument will serve as a shared resource used by many laboratories within the NHLBI-DIR and, to a lesser extent, investigators across the NIH. The Leica Microsystems can provide all of the required capabilities within a single integrated system, ensuring compatibility with existing workflows, user training, and experimental protocols. The enhanced capabilities are essential to meet growing demand and to support complex, high-impact research projects requiring advanced, multi-parameter and spatially resolved imaging technologies. 2.2 Objective The objective of this acquisition is to obtain a Microscope System with Confocal, 3D-STED, FLIM, and Spectral Multiplexing imaging capabilities that integrate all of the required imaging modalities within one uni?ed and fully supported instrument con?guration. 3. Product Speci?cations/Features/Salient Characteristics Required Minimum Speci?cations: Confocal excitation: white light laser with tunable excitation range 440–790 nm with Acousto optical beam splitter system. Prism-based ?uorescence detection: prism-based spectral detection with variable emission windows to 850 nm. Detectors: ?ve (5) Hybrid (HyD) detectors optimized for spectral detection across approximately 400–850 nm. The proposed system must provide advanced confocal imaging capability and shall include a white light laser (WLL) with continuously tunable excitation from 440–790 nm integrated with acousto-optical beam splitter (AOBS) technology. The system must incorporate prism-based spectral emission detection with fully adjustable emission bandwidth selection and detection spanning 400–850 nm, along with a minimum of ?ve (5) Hybrid (HyD) detectors appropriately matched and optimized for the emission bandwidth being measured across the full spectral detection range to ensure maximal sensitivity and signal ?delity. The overall con?guration shall maximize excitation ?exibility, spectral se...